Standing
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | İskenderunspor | 5 | 5 | 0 | 0 | 8 | 2 | +6 | 15 |
| 2 | Karacabey Bele… | 5 | 3 | 2 | 0 | 8 | 2 | +6 | 11 |
| 3 | Serik Belediyespor | 5 | 2 | 3 | 0 | 7 | 3 | +4 | 9 |
| 4 | Kocaelispor | 5 | 2 | 3 | 0 | 7 | 5 | +2 | 9 |
| 5 | Bucaspor 1928 | 5 | 2 | 3 | 0 | 4 | 2 | +2 | 9 |
| 6 | Etimesgut Bele… | 5 | 2 | 2 | 1 | 8 | 4 | +4 | 8 |
| 7 | Vanspor FK | 5 | 2 | 2 | 1 | 6 | 4 | +2 | 8 |
| 8 | 1461 Trabzon FK | 5 | 2 | 2 | 1 | 4 | 3 | +1 | 8 |
| 9 | Zonguldak Kömü… | 5 | 2 | 1 | 2 | 8 | 6 | +2 | 7 |
| 10 | Sarıyer | 5 | 1 | 3 | 1 | 7 | 7 | +0 | 6 |
| 11 | Kırklarelispor | 5 | 1 | 3 | 1 | 4 | 4 | +0 | 6 |
| 12 | Ankara Demirspor | 5 | 1 | 3 | 1 | 3 | 3 | +0 | 6 |
| 13 | Fethiyespor | 5 | 2 | 0 | 3 | 8 | 9 | -1 | 6 |
| 14 | Kastamonuspor | 5 | 1 | 2 | 2 | 4 | 5 | -1 | 5 |
| 15 | Balıkesirspor | 5 | 1 | 1 | 3 | 5 | 8 | -3 | 4 |
| 16 | Diyarbekirspor | 5 | 1 | 1 | 3 | 7 | 11 | -4 | 4 |
| 17 | Uşak Spor | 5 | 0 | 3 | 2 | 3 | 7 | -4 | 3 |
| 18 | Kırşehir FK | 5 | 0 | 3 | 2 | 2 | 6 | -4 | 3 |
| 19 | Adıyaman | 5 | 0 | 2 | 3 | 1 | 6 | -5 | 2 |
| 20 | Pazarspor | 5 | 0 | 1 | 4 | 3 | 10 | -7 | 1 |
Fixtures
| September 24, 2022 | ||
| Ankaraspor | 15:30 | Somaspor |
| İnegölspor | 16:00 | Isparta 32 Spor |
| Esenler Erokspor | 16:00 | Nazilli Beledi… |
| Uşak Spor | 16:00 | Kocaelispor |
| Balıkesirspor | 19:00 | Ankara Demirspor |
| September 25, 2022 | ||
| 1461 Trabzon FK | 15:00 | Karacabey Bele… |
| Pazarspor | 15:00 | Kastamonuspor |
| Sivas Belediyespor | 15:00 | Afyonspor |
| Bayburt ÖİS | 15:00 | Arnavutköy Bel… |
| Adıyaman | 15:00 | Diyarbekirspor |
| Zonguldak Kömü… | 15:30 | İskenderunspor |
| Sarıyer | 16:00 | Serik Belediyespor |
| Kırklarelispor | 16:00 | Vanspor FK |
| Fethiyespor | 19:00 | Etimesgut Bele… |
| Çorum FK | 19:00 | Batman Petrolspor |
| Amed | 19:00 | Bursaspor |
| Bucaspor 1928 | 19:00 | Kırşehir FK |
| 24 Erzincanspor | 19:00 | Menemen |
| Tarsus İdman Yurdu | 19:00 | Şanlıurfaspor |
Result
| September 18, 2022 | ||
| Isparta 32 Spor | 1 - 0 | Bayburt ÖİS |
| Menemen | 2 - 1 | İnegölspor |
| Şanlıurfaspor | 0 - 0 | Ankaraspor |
| Bursaspor | 6 - 0 | Sivas Belediyespor |
| Afyonspor | 2 - 1 | Çorum FK |
| Karacabey Bele… | 2 - 1 | Fethiyespor |
| Diyarbekirspor | 1 - 2 | 1461 Trabzon FK |
| İskenderunspor | 1 - 0 | Adıyaman |
| Arnavutköy Bel… | 0 - 1 | Tarsus İdman Yurdu |
| Nazilli Beledi… | 3 - 3 | Amed |
| Somaspor | 2 - 1 | Esenler Erokspor |
| Kocaelispor | 1 - 1 | Bucaspor 1928 |
| Kastamonuspor | 1 - 0 | Balıkesirspor |
| Kırşehir FK | 1 - 1 | Sarıyer |
| Düzcespor | 0 - 2 | 24 Erzincanspor |
| Serik Belediyespor | 1 - 1 | Kırklarelispor |
| Ankara Demirspor | 1 - 1 | Uşak Spor |
| Vanspor FK | 3 - 1 | Zonguldak Kömü… |
| Etimesgut Bele… | 2 - 0 | Pazarspor |