Standing
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Real Madrid | 6 | 6 | 0 | 0 | 17 | 6 | +11 | 18 |
| 2 | Barcelona | 6 | 5 | 1 | 0 | 18 | 1 | +17 | 16 |
| 3 | Real Betis | 6 | 5 | 0 | 1 | 10 | 4 | +6 | 15 |
| 4 | Athletic Bilbao | 6 | 4 | 1 | 1 | 12 | 4 | +8 | 13 |
| 5 | Osasuna | 6 | 4 | 0 | 2 | 7 | 5 | +2 | 12 |
| 6 | Villarreal | 6 | 3 | 2 | 1 | 10 | 2 | +8 | 11 |
| 7 | Atlético de Madrid | 6 | 3 | 1 | 2 | 10 | 6 | +4 | 10 |
| 8 | Real Sociedad | 6 | 3 | 1 | 2 | 7 | 8 | -1 | 10 |
| 9 | Valencia | 6 | 3 | 0 | 3 | 10 | 5 | +5 | 9 |
| 10 | Mallorca | 6 | 2 | 2 | 2 | 6 | 7 | -1 | 8 |
| 11 | Girona | 6 | 2 | 1 | 3 | 7 | 7 | +0 | 7 |
| 12 | Rayo Vallecano | 6 | 2 | 1 | 3 | 7 | 8 | -1 | 7 |
| 13 | Celta Vigo | 6 | 2 | 1 | 3 | 8 | 13 | -5 | 7 |
| 14 | Getafe | 6 | 2 | 1 | 3 | 6 | 12 | -6 | 7 |
| 15 | Sevilla | 6 | 1 | 2 | 3 | 7 | 11 | -4 | 5 |
| 16 | Almeria | 6 | 1 | 1 | 4 | 4 | 7 | -3 | 4 |
| 17 | Espanyol | 6 | 1 | 1 | 4 | 7 | 12 | -5 | 4 |
| 18 | Real Valladolid | 6 | 1 | 1 | 4 | 3 | 11 | -8 | 4 |
| 19 | Cadiz | 6 | 1 | 0 | 5 | 1 | 14 | -13 | 3 |
| 20 | Elche | 6 | 0 | 1 | 5 | 2 | 16 | -14 | 1 |
Fixtures
| September 30, 2022 | ||
| Athletic Bilbao | 22:00 | Almeria |
| October 1, 2022 | ||
| Cadiz | 15:00 | Villarreal |
| Getafe | 17:15 | Real Valladolid |
| Sevilla | 19:30 | Atlético de Madrid |
| Mallorca | 22:00 | Barcelona |
| October 2, 2022 | ||
| Espanyol | 15:00 | Valencia |
| Celta Vigo | 17:15 | Real Betis |
| Girona | 19:30 | Real Sociedad |
| Real Madrid | 22:00 | Osasuna |
| October 3, 2022 | ||
| Rayo Vallecano | 22:00 | Elche |
| October 7, 2022 | ||
| Osasuna | 22:00 | Valencia |
| October 8, 2022 | ||
| Almeria | 15:00 | Rayo Vallecano |
| Atlético de Madrid | 17:15 | Girona |
| Sevilla | 19:30 | Athletic Bilbao |
| Getafe | 22:00 | Real Madrid |
| October 9, 2022 | ||
| Real Valladolid | 15:00 | Real Betis |
| Cadiz | 17:15 | Espanyol |
| Real Sociedad | 19:30 | Villarreal |
| Barcelona | 22:00 | Celta Vigo |
| October 10, 2022 | ||
| Elche | 22:00 | Mallorca |
| September 18, 2022 | ||
| Atlético de Madrid | 1 - 2 | Real Madrid |
| Real Sociedad | 2 - 1 | Espanyol |
| Real Betis | 2 - 1 | Girona |
| Villarreal | 1 - 1 | Sevilla |
| Osasuna | 0 - 2 | Getafe |
| September 17, 2022 | ||
| Athletic Bilbao | 3 - 2 | Rayo Vallecano |
| Valencia | 3 - 0 | Celta Vigo |
| Barcelona | 3 - 0 | Elche |
| Mallorca | 1 - 0 | Almeria |
| September 16, 2022 | ||
| Real Valladolid | 0 - 1 | Cadiz |
| September 12, 2022 | ||
| Almeria | 0 - 1 | Osasuna |
| September 11, 2022 | ||
| Real Betis | 1 - 0 | Villarreal |
| Getafe | 2 - 1 | Real Sociedad |
| Elche | 1 - 4 | Athletic Bilbao |
| Real Madrid | 4 - 1 | Mallorca |
| September 10, 2022 | ||
| Atlético de Madrid | 4 - 1 | Celta Vigo |
| Cadiz | 0 - 4 | Barcelona |
| Espanyol | 2 - 3 | Sevilla |
| Rayo Vallecano | 2 - 1 | Valencia |
| September 9, 2022 | ||
| Girona | 2 - 1 | Real Valladolid |