Standing
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Leones | 14 | 8 | 3 | 3 | 21 | 10 | +11 | 27 |
| 2 | Fortaleza CEIF | 14 | 7 | 4 | 3 | 26 | 17 | +9 | 25 |
| 3 | Deportes Quindío | 14 | 6 | 7 | 1 | 17 | 8 | +9 | 25 |
| 4 | Real Cartagena | 14 | 7 | 4 | 3 | 19 | 16 | +3 | 25 |
| 5 | Tigres | 14 | 6 | 4 | 4 | 16 | 12 | +4 | 22 |
| 6 | Boyacá Chicó | 14 | 6 | 4 | 4 | 18 | 16 | +2 | 22 |
| 7 | Llaneros | 14 | 6 | 4 | 4 | 14 | 12 | +2 | 22 |
| 8 | Bogotá | 14 | 6 | 4 | 4 | 17 | 16 | +1 | 22 |
| 9 | Valledupar | 14 | 5 | 6 | 3 | 15 | 12 | +3 | 21 |
| 10 | Orsomarso | 14 | 5 | 3 | 6 | 14 | 20 | -6 | 18 |
| 11 | Atlético | 14 | 3 | 5 | 6 | 10 | 14 | -4 | 14 |
| 12 | Real Santander | 14 | 2 | 5 | 7 | 13 | 21 | -8 | 11 |
| 13 | Barranquilla | 14 | 2 | 4 | 8 | 13 | 23 | -10 | 10 |
| 14 | Atlético Huila | 14 | 1 | 6 | 7 | 7 | 14 | -7 | 9 |
| 15 | Boca Juniors d… | 14 | 1 | 5 | 8 | 10 | 19 | -9 | 8 |
Fixtures
| September 23, 2022 | ||
| Atlético | 23:00 | Deportes Quindío |
| Bogotá | 23:00 | Orsomarso |
| September 24, 2022 | ||
| Cúcuta Deportivo | 00:00 | Real Santander |
| Boyacá Chicó | 04:00 | Fortaleza CEIF |
| Valledupar | 23:00 | Leones |
| Llaneros | 23:30 | Tigres |
| September 25, 2022 | ||
| Barranquilla | 01:00 | Real Cartagena |
| September 27, 2022 | ||
| Boca Juniors d… | 23:00 | Atlético |
| September 28, 2022 | ||
| Deportes Quindío | 23:00 | Atlético Huila |
| September 30, 2022 | ||
| Orsomarso | 23:00 | Fortaleza CEIF |
| October 1, 2022 | ||
| Tigres | 02:00 | Bogotá |
| Valledupar | 23:00 | Barranquilla |
| October 2, 2022 | ||
| Real Cartagena | 00:00 | Boca Juniors d… |
| October 3, 2022 | ||
| Llaneros | 23:00 | Deportes Quindío |
| Real Santander | 23:00 | Atlético Huila |
| October 4, 2022 | ||
| Atlético | 02:00 | Cúcuta Deportivo |
| October 5, 2022 | ||
| Leones | 03:40 | Boyacá Chicó |
Result
| September 20, 2022 | ||
| Atlético | 3 - 2 | Barranquilla |
| Real Cartagena | 3 - 1 | Deportes Quindío |
| September 19, 2022 | ||
| Real Santander | 0 - 0 | Boyacá Chicó |
| Atlético Huila | 2 - 0 | Bogotá |
| Cúcuta Deportivo | 2 - 1 | Valledupar |
| September 18, 2022 | ||
| Orsomarso | 1 - 4 | Leones |
| Tigres | 3 - 2 | Boca Juniors d… |
| September 17, 2022 | ||
| Fortaleza CEIF | 1 - 0 | Llaneros |
| September 15, 2022 | ||
| Atlético | 0 - 2 | Real Cartagena |
| September 14, 2022 | ||
| Deportes Quindío | 2 - 0 | Cúcuta Deportivo |
| Barranquilla | 2 - 1 | Real Santander |
| September 13, 2022 | ||
| Boyacá Chicó | 0 - 2 | Bogotá |
| Leones | 2 - 2 | Atlético Huila |
| September 12, 2022 | ||
| Tigres | 1 - 0 | Orsomarso |
| September 11, 2022 | ||
| Boca Juniors d… | 0 - 0 | Fortaleza CEIF |
| Llaneros | 2 - 0 | Real Cartagena |
| Valledupar | 1 - 0 | Atlético |
| September 9, 2022 | ||
| Deportes Quindío | 0 - 0 | Boyacá Chicó |
| Atlético Huila | 3 - 2 | Cúcuta Deportivo |
| September 8, 2022 | ||
| Bogotá | 4 - 1 | Boca Juniors d… |