Standing
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cruzeiro | 30 | 19 | 8 | 3 | 41 | 16 | +25 | 65 |
| 2 | Bahia | 30 | 15 | 6 | 9 | 33 | 19 | +14 | 51 |
| 3 | Grêmio | 30 | 13 | 11 | 6 | 34 | 20 | +14 | 50 |
| 4 | Vasco da Gama | 30 | 13 | 9 | 8 | 35 | 25 | +10 | 48 |
| 5 | Londrina | 30 | 12 | 9 | 9 | 30 | 27 | +3 | 45 |
| 6 | Sport Recife | 30 | 11 | 10 | 9 | 24 | 22 | +2 | 43 |
| 7 | Ituano | 30 | 10 | 11 | 9 | 33 | 28 | +5 | 41 |
| 8 | Ponte Preta | 30 | 10 | 10 | 10 | 27 | 26 | +1 | 40 |
| 9 | CRB | 30 | 10 | 10 | 10 | 28 | 35 | -7 | 40 |
| 10 | Criciúma | 30 | 9 | 13 | 8 | 30 | 26 | +4 | 40 |
| 11 | Tombense | 30 | 9 | 13 | 8 | 28 | 32 | -4 | 40 |
| 12 | Sampaio Corrêa | 30 | 10 | 9 | 11 | 34 | 34 | +0 | 39 |
| 13 | Novorizontino | 30 | 9 | 9 | 12 | 31 | 35 | -4 | 36 |
| 14 | Chapecoense | 30 | 8 | 11 | 11 | 27 | 28 | -1 | 35 |
| 15 | Vila Nova | 30 | 6 | 16 | 8 | 22 | 27 | -5 | 34 |
| 16 | Guarani | 30 | 7 | 11 | 12 | 23 | 32 | -9 | 32 |
| 17 | CSA | 30 | 6 | 14 | 10 | 21 | 29 | -8 | 32 |
| 18 | Brusque | 30 | 8 | 7 | 15 | 19 | 27 | -8 | 31 |
| 19 | Operário PR | 30 | 7 | 9 | 14 | 23 | 36 | -13 | 30 |
| 20 | Náutico | 30 | 7 | 6 | 17 | 25 | 44 | -19 | 27 |
Fixtures
| September 21, 2022 | ||
| Grêmio | 01:00 | Sport Recife |
| Guarani | 03:30 | Novorizontino |
| September 22, 2022 | ||
| Cruzeiro | 03:00 | Vasco da Gama |
| September 23, 2022 | ||
| Vila Nova | 03:30 | CRB |
| September 24, 2022 | ||
| Náutico | 01:00 | Sampaio Corrêa |
| Londrina | 03:30 | Ponte Preta |
| Ituano | 17:00 | Brusque |
| September 25, 2022 | ||
| Bahia | 00:15 | Operário PR |
| September 26, 2022 | ||
| Criciúma | 00:15 | Chapecoense |
| September 27, 2022 | ||
| CSA | 02:00 | Tombense |
| September 29, 2022 | ||
| Ponte Preta | 01:00 | Cruzeiro |
| September 30, 2022 | ||
| Tombense | 01:00 | Novorizontino |
| Vasco da Gama | 03:30 | Londrina |
| October 1, 2022 | ||
| CSA | 01:00 | Guarani |
| Operário PR | 01:00 | Vila Nova |
| Sampaio Corrêa | 01:00 | Grêmio |
| Chapecoense | 03:30 | Bahia |
| Brusque | 17:00 | Criciúma |
| Sport Recife | 21:00 | Náutico |
| October 2, 2022 | ||
| Ituano | 00:30 | CRB |
Result
| September 18, 2022 | ||
| CRB | 0 - 2 | Cruzeiro |
| Sampaio Corrêa | 1 - 1 | Criciúma |
| September 17, 2022 | ||
| Brusque | 0 - 1 | Vila Nova |
| Chapecoense | 1 - 0 | CSA |
| Tombense | 1 - 1 | Londrina |
| Novorizontino | 2 - 0 | Grêmio |
| Vasco da Gama | 4 - 1 | Náutico |
| September 14, 2022 | ||
| Ponte Preta | 1 - 1 | Ituano |
| Operário PR | 0 - 1 | Guarani |
| September 13, 2022 | ||
| Sport Recife | 1 - 0 | Bahia |
| September 11, 2022 | ||
| Grêmio | 2 - 1 | Vasco da Gama |
| Londrina | 2 - 1 | Chapecoense |
| September 10, 2022 | ||
| CSA | 1 - 1 | CRB |
| Ituano | 3 - 0 | Tombense |
| Náutico | 1 - 0 | Brusque |
| September 9, 2022 | ||
| Cruzeiro | 1 - 0 | Operário PR |
| Criciúma | 0 - 0 | Bahia |
| September 8, 2022 | ||
| Sampaio Corrêa | 2 - 1 | Novorizontino |
| Ponte Preta | 1 - 0 | Sport Recife |
| September 7, 2022 | ||
| Vila Nova | 2 - 1 | Guarani |