Standing
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Midland | 18 | 9 | 7 | 2 | 31 | 16 | +15 | 34 |
| 2 | Excursionistas | 18 | 8 | 8 | 2 | 25 | 14 | +11 | 32 |
| 3 | Berazategui | 18 | 9 | 4 | 5 | 22 | 16 | +6 | 31 |
| 4 | Sportivo Italiano | 18 | 8 | 5 | 5 | 22 | 13 | +9 | 29 |
| 5 | Claypole | 18 | 8 | 5 | 5 | 16 | 15 | +1 | 29 |
| 6 | Leandro Nicéfo… | 18 | 7 | 7 | 4 | 18 | 14 | +4 | 28 |
| 7 | Real Pilar | 18 | 8 | 4 | 6 | 17 | 13 | +4 | 28 |
| 8 | Deportivo Español | 18 | 7 | 6 | 5 | 25 | 16 | +9 | 27 |
| 9 | Deportivo Lafe… | 18 | 5 | 12 | 1 | 9 | 5 | +4 | 27 |
| 10 | Atlas | 18 | 7 | 6 | 5 | 19 | 16 | +3 | 27 |
| 11 | Luján | 18 | 6 | 8 | 4 | 19 | 18 | +1 | 26 |
| 12 | Liniers | 18 | 7 | 4 | 7 | 24 | 21 | +3 | 25 |
| 13 | General Lamadrid | 18 | 7 | 4 | 7 | 23 | 24 | -1 | 25 |
| 14 | Central Córdoba | 18 | 4 | 8 | 6 | 18 | 19 | -1 | 20 |
| 15 | Argentino Merlo | 18 | 5 | 5 | 8 | 15 | 21 | -6 | 20 |
| 16 | Victoriano Arenas | 18 | 5 | 3 | 10 | 15 | 28 | -13 | 18 |
| 17 | San Martín Burzaco | 18 | 1 | 8 | 9 | 14 | 28 | -14 | 11 |
| 18 | El Porvenir | 18 | 2 | 5 | 11 | 10 | 24 | -14 | 11 |
| 19 | Puerto Nuevo | 18 | 1 | 5 | 12 | 10 | 31 | -21 | 8 |
Fixtures
| July 10, 2022 | ||
| Luján | 21:30 | Leandro Nicéfo… |
| September 24, 2022 | ||
| San Martín Burzaco | 21:30 | Liniers |
| Leandro Nicéfo… | 21:30 | Deportivo Español |
| Sportivo Italiano | 21:30 | Central Córdoba |
| Real Pilar | 21:30 | Excursionistas |
| September 25, 2022 | ||
| Puerto Nuevo | 21:30 | Luján |
| Argentino Merlo | 21:30 | Victoriano Arenas |
| El Porvenir | 21:30 | Midland |
| September 26, 2022 | ||
| Berazategui | 21:30 | Claypole |
| General Lamadrid | 21:30 | Atlas |
| October 1, 2022 | ||
| Claypole | 03:00 | General Lamadrid |
| Luján | 03:00 | Argentino Merlo |
| Victoriano Arenas | 03:00 | Berazategui |
| Deportivo Lafe… | 03:00 | Puerto Nuevo |
| Atlas | 03:00 | Real Pilar |
| Liniers | 03:00 | El Porvenir |
| Midland | 03:00 | Leandro Nicéfo… |
| Deportivo Español | 03:00 | Sportivo Italiano |
| Excursionistas | 03:00 | San Martín Burzaco |
Result
| September 19, 2022 | ||
| Luján | 1 - 4 | Deportivo Lafe… |
| Midland | 0 - 1 | San Martín Burzaco |
| September 18, 2022 | ||
| Victoriano Arenas | 0 - 0 | Puerto Nuevo |
| Claypole | 1 - 2 | Argentino Merlo |
| Atlas | 1 - 0 | Berazategui |
| Excursionistas | 2 - 0 | General Lamadrid |
| Central Córdoba | 3 - 0 | Leandro Nicéfo… |
| September 17, 2022 | ||
| Liniers | 0 - 2 | Real Pilar |
| Deportivo Español | 3 - 1 | El Porvenir |
| September 14, 2022 | ||
| San Martín Burzaco | 1 - 2 | Deportivo Español |
| General Lamadrid | 1 - 1 | Liniers |
| Berazategui | 2 - 0 | Excursionistas |
| September 13, 2022 | ||
| Argentino Merlo | 2 - 0 | Atlas |
| Puerto Nuevo | 2 - 1 | Claypole |
| Deportivo Lafe… | 1 - 0 | Victoriano Arenas |
| Real Pilar | 1 - 1 | Midland |
| El Porvenir | 0 - 0 | Central Córdoba |
| Leandro Nicéfo… | 0 - 2 | Sportivo Italiano |
| September 11, 2022 | ||
| Liniers | 1 - 3 | Berazategui |